ORIGINAL ARTICLE: PDF OnlyDEROSE JOSEPH J. JR.; UMANA, JUAN P.; MADIGAN, JOHN D.; KLINGER, JOHN F.; JARVIK, ROBERT K.; SUN, BENJAMIN C.; ROSE, ERIC A.; OZ, MEHMET C.ASAIO Journal: September-October 1997 - p M427 Free Abstract Cardiopulmonary bypass (CPB) causes a well described systemic inflammatory response. To avoid these potential detrimental effects, coronary artery bypass grafting (CABG) has been attempted off CPB on the beating heart. With the use of a left ventricular (LV) assist device during CABG, the heart can be made flaccid with β-blockade, and the systemic circulation can continue to be supported. The hemodynamic and hematologic consequences of left heart bypass with a miniature axial flow pump were studied in a sheep CABG model. © Lippincott-Raven Publishers.
