Technical ArticleCulture Cell Block Controls as a Tool to the Biomolecular Diagnosis of Infectious DiseasesJosé Tadeu de Araujo, Leonardo BSc, MSc, PhD*; Salas-Gómez, David DVM, MSc*; Midori Kimura, Lidia BSc*; Fernandes Possatto Takahashi, Juliana BSc, MSc, PhD*; de Souza Barrel, Joana BSc*; Rollin, Dominique C. MD†; Mariotti Guerra, Juliana DVM, MSc, PhD*Author Information *Pathology Center, Adolfo Lutz Institute, São Paulo, Brazil †Infectious Diseases Pathology Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA The authors declare no conflict of interest. Reprints: Leonardo José Tadeu de Araujo, BSc, MSc, PhD, Laboratory of Quantitative Pathology of the Pathology Center of Adolfo Lutz Institute, Avenida Doutor Arnaldo No. 355-7° andar-Laboratório 705, Cerqueira César CEP 01246-902, São Paulo, Brazil (e-mail: email@example.com). Applied Immunohistochemistry & Molecular Morphology: July 2020 - Volume 28 - Issue 6 - p 484-487 doi: 10.1097/PAI.0000000000000811 Buy Metrics Abstract The cell block (CB) technique has allowed easy obtainment of samples such as cellular and culture suspensions, to perform specific molecular tests such as immunohistochemistry and in situ hybridization. It has been improved along time, accuracy, and quality of the diagnoses, however, the cost of a commercial gel matrix for the preparation of CB is high and not suitable depending on the situation. The objective of this study is to test agarose as an alternative to the commercial gel matrix in the preparation of Aspergillus fumigatus’ CB. Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.