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Metastatic Acinic Cell Carcinoma to the Vagina

A First Reported Case

Hom, Marianne, MD*; Fong, Andrew, MD; Sanford, Melissa, MD; Mhawech-Fauceglia, Paulette, MD*,†

Applied Immunohistochemistry & Molecular Morphology: April 2019 - Volume 27 - Issue 4 - p e39–e41
doi: 10.1097/PAI.0000000000000570
Online Articles: Case Report

This is a case of a 62-year-old woman with a remote history of acinic cell carcinoma of the parotid gland, who presented with a palpable vaginal mass, anterior vaginal wall prolapse, and stress urinary incontinence. A 2 cm firm mobile mass on the anterior vaginal wall was found on clinical examination. A computed tomographic scan revealed a mass between the vaginal vault and bladder that was eventually surgically excised. The histology, supported by the immunohistochemistry, revealed metastatic acinic cell carcinoma to the vagina after 37 years of her initial diagnosis. This is the first reported case in the literature to occur in the vagina.

*Department of Obstetrics and Gynecology, Los Angeles County+University of Southern California Medical Center

Departments of Pathology

Urology, University of Southern California (USC), Los Angeles, CA

The authors declare no conflict of interest.

Reprints: Paulette Mhawech-Fauceglia, MD, University of Southern California Outpatient Tower, 7th floor, Los Angeles, CA 90033 (e-mail:

Received June 28, 2017

Accepted June 29, 2017

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