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Acute Postoperative Endophthalmitis Following Cataract Surgery: A Review

Pathengay, Avinash FRCS*†; Khera, Manav MS; Das, Taraprasad MD, FRCS; Sharma, Savitri MD, FAMS§; Miller, Darlene DHSc, MPH*; Flynn, Harry W. Jr MD*

The Asia-Pacific Journal of Ophthalmology: January/February 2012 - Volume 1 - Issue 1 - p 35–42
doi: 10.1097/APO.0b013e31823e574b
Review Article

Endophthalmitis following cataract surgery is rare but continues to be a serious complication following cataract surgery. Over the years, the incidence of endophthalmitis has declined because of various preoperative and perioperative measures. They include use of antiseptic and appropriate surgical draping techniques. In this review, we have focused on the incidence, existing risk factors, various clinical features, management strategies, and prophylaxis pertaining to postoperative endophthalmitis following cataract surgery. Outcomes and pitfalls of 2 landmark studies, namely, the Endophthalmitis Vitrectomy Study and the European Society of Cataract and Refractive Surgeons Endophthalmitis Study, are briefly mentioned.

Infectious endophthalmitis following cataract surgery is a dreaded complication. Preoperative identification of risk factors and effective prophylaxis could help in reducing its incidence. Early diagnosis followed by management of these patients either with vitreous tap or vitrectomy coupled with intravitreal antibiotics holds the key.

From the *Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL; †Department of Retina and Vitreous Surgery, L V Prasad Eye Institute, GMRV Campus, Visakhapatnam, Andhra Pradesh; and Department of ‡Retina and Vitreous and §Ocular Microbiology Laboratory, L. V. Prasad Eye Institute, Bhubaneswar, Orissa, India.

Received for publication June 18, 2011, and accepted August 12, 2011.

Reprints: Harry W. Flynn, Jr, MD, Bascom Palmer Eye Institute, 900 NW 17th St, Miami, FL 33136. E-mail:; or Taraprasad Das, MD, FRCS, L V Prasad Eye Institute, Patia, Bhubaneswar 751 024 India. E-mail:

The study was supported by the National Institute of Health Center grant P30-EY014801, an unrestricted grant to the University of Miami from Research to Prevent Blindness, New York, and the Hyderabad Eye Research Foundation, Hyderabad, Andhra Pradesh, India.

The authors have no funding or conflicts of interest to declare.

© 2012Asia-Pacific Academy of Ophthalmology
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