CASE REPORTDramatic prostate-specific antigen response with activated hemicellulose compound in metastatic castration-resistant prostate cancerTurner, Jeffreya; Chaudhary, UzairbAuthor Information aDivision of Hematology/Oncology, Department of Medicine, Medical University of South Carolina, Charleston bLowcountry Hematology and Oncology, South Carolina, USA Correspondence to Uzair B. Chaudhary, MD, Lowcountry Hematology and Oncology, SC 29464, USA Tel: +1 843 881 5844; fax: +1 843 881 9499; e-mail: [email protected] Received 22 April 2008 Revised form accepted 25 August 2008 Anti-Cancer Drugs: March 2009 - Volume 20 - Issue 3 - p 215-216 doi: 10.1097/CAD.0b013e3283163c26 Buy Metrics Abstract Castration-resistant prostate cancer (CRPC) is an incurable disease with limited treatment options. Herbal supplements are unconventional treatments for a variety of diseases. Active hemicellulose compound (AHCC) is a Japanese supplement discovered by hybridizing several mushrooms used in traditional healing for the purpose of maintaining ‘super immunity’. We report on a 66-year-old gentleman with CRPC with an excellent serologic response to AHCC. This case hypothesizes that AHCC may have potential activity against CRPC. © 2009 Lippincott Williams & Wilkins, Inc.