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Breast Reduction Following Hormonal Therapy in a Transgender Female Patient

Margulies, Ilana G. MS; Xu, Hope BA; Kozato, Aki BS; Facque, Alexander MD; Taub, Peter J. MD, MS

doi: 10.1097/SAP.0000000000001855
Breast Surgery: PDF Only

In male-to-female gender transition, individuals request a number of interventions, including hormonal therapy, to promote feminizing characteristics. Estrogen-based medication is prescribed to increase breast development, decrease facial hair, promote feminine adipose tissue deposition, and soften skin. Surgical breast augmentation to supplement unsatisfying breast growth after hormonal therapy is a common and well-studied course of management for such transgender patients. In a departure from convention, the authors present a case of symptomatic macromastia requiring surgical breast reduction in a transgender woman following 24 years of hormonal therapy and illicit silicone injections in multiple areas of her body, including the breasts.

From the Division of Plastic and Reconstructive Surgery, Icahn School of Medicine at Mount Sinai, New York, NY.

Received October 15, 2018, and accepted for publication, after revision December 29, 2018.

Conflicts of interest and sources of funding: none declared.

I.G.M. and H.X. contributed equally to this study.

Reprints: Ilana G. Margulies, MS, 5 East 98th St, Box 1259 New York, NY 10029. E-mail:

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