Review PapersSecondary Lymphedema Following Radical Prostatectomy Noncontrast Magnetic Resonance Lymphangiography Assessment and Vascularized Lymph Node TransferCellina, Michaela MDa; Martinenghi, Carlo MDb; Gibelli, Daniele PhDc; Menozzi, Andrea MDd; Soresina, Massimo MDd; Boccanera, Dario MDd; Giardini, Denisa MDe; Oliva, Giancarlo MDaAuthor Information From the aU.O. Radiologia, ASST Fatebenefratelli Sacco, Milano bU.O. Radiologia, IRCCS Ospedale San Raffaele cDipartimento di Scienze Biometriche, Università degli Studi di Milano dU.O. Chirurgia Plastica, ASST Fatebenefratelli Sacco eCasa di Cura La Madonnina, Milano, Italy. Received March 26, 2019, and accepted for publication, after revision September 4, 2019. Conflicts of interest and sources of funding: none. Reprints: Michaela Cellina, MD, Department of Radiology, ASST Fatebenefratelli Sacco, piazza Principessa Clotilde 3, 20121 Milan, Italy. E-mail: [email protected]. Annals of Plastic Surgery: November 2020 - Volume 85 - Issue 5 - p e12-e18 doi: 10.1097/SAP.0000000000002149 Buy Metrics Abstract Lymphedema (LE) is a progressive chronic disorder, frequently related to malignancies and their treatment in Western countries. It markedly affected patients' quality of life, and its management is challenging, mainly based on conservative therapy, as bandages and manual lymphatic drainage, with limited results. Recent advances in imaging technology and microsurgical techniques have changed the approach to this disorder, particularly the recent application of magnetic resonance for the study of LE and the increasingly widespread use of surgical interventions, such as vascularized lymph node transfer. As secondary LE due to radical prostatectomy and/or radiation treatment is a frequent cause of chronic disability in the male population, and few data are available in literature about which imaging technique can be applied to diagnose it and about the surgical modalities to treat this condition, we want to propose an overview on the lymphatic vessels anatomy and function, on the applications of noncontrast magnetic resonance lymphangiography and about the pieces of information this examination can provide, and on the technique of vascularized lymph node transfer and the rationale of this surgical procedure in secondary LE related to prostatic malignancy treatment. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.