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Rosai-Dorfman Disease

Cutaneous and Parotid Involvement

Karami, Reem, MD; Ghieh, Fadi, MD; Baroud, Joe, MD; Abu Sittah, Ghassan, MBchB, FRCS

doi: 10.1097/SAP.0000000000001794
Head and Neck Surgery

Rosai-Dorfman disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy, is a rare and benign proliferative disease that affects histiocytes. Its etiology remains unclear. Rosai-Dorfman disease primarily affects lymph nodes with many extranodal manifestations present, including cutaneous, pulmonary, ophthalmic, and gastrointestinal. Diagnosis is mainly histologic with the presence of Rosai-Dorfman cells, which demonstrate emperipolesis. We report a case of a 30-year-old man who presented with a facial cutaneous mass and was diagnosed with RDD; he underwent surgical excision. The patient experienced recurrent lesions on the surgical scar and parotid gland as well as the lower back. Treatment consisted of systemic steroids and surgical excision.

From the Division of Plastic and Reconstructive Surgery, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon.

Received September 21, 2018, and accepted for publication, after revision November 7, 2018.

Conflicts of interest and sources of funding: none declared.

Reprints: Ghassan Abu Sittah, MBchB, FRCS, Department of Surgery American University of Beirut Medical Center, P.O. Box 11-0236 Riad El Solh, Beirut 1107-2020, Lebanon. E-mail:

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