Clinical PapersIntracompartmental Sepsis With Burn A Case ReportChou, Chieh MD; Lee, Su-shin MD; Wang, Hui-Min PhD; Hsieh, Tung-Ying MD; Lee, Hsiao-Chen MD; Chang, Chih-Hau MD; Lai, Chung-Sheng MD; Chang, Kao-Ping MD, PhD; Lin, Sin-Daw MD, PhD; Huang, Shu-Hung MDAuthor Information From Kaohsiung Medical University Hospital, Koahsiung Medical University, Kaohsiung, Taiwan. Received October 22, 2015, and accepted for publication, after revision November 7, 2015. Conflicts of interest and sources of funding: none declared. Reprints: Shu-Hung Huang, MD, Division of Plastic Surgery, Kaohsiung Medical University Hospital, 19 Fl, No 100, Tz-You 1st Road, Kaohsiung 807, Taiwan. E-mail: email@example.com. Annals of Plastic Surgery: March 2016 - Volume 76 - Issue - p S25-S28 doi: 10.1097/SAP.0000000000000691 Buy Metrics Abstract Intracompartmental sepsis (IS) is a rare complication in patients with burns. Intracompartmental sepsis presents in patients with inadequate perfusion of intracompartmental tissues and subsequent ischemic necrosis and infection. Contributing factors include high-volume resuscitation, delayed escharotomies, and previous bacteremia. We describe a case of massive burns from a gas explosion and the subsequent development of IS in our intensive care burn unit. The patient presented with a 75% total body surface area burn on admission, with 39% superficial, deep partial-thickness and 26% full-thickness burns. Intracompartmental sepsis was diagnosed 45 days after admission. Anterior compartment muscles, including the tibialis anterior, extensor hallucis longus, and extensor digitorum longus, were necrotic with relatively fair nerve and vascular structures. Intracompartmental sepsis is an overwhelming, infectious complication that appears late and can occur easily in patients with major burns. Early diagnosis and management are a must for improving outcomes. Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved.