Clinical PapersGlomus Tumor Twenty-Year Experience and Literature ReviewChou, Tingmao MD; Pan, Shin Chen MD, PhD; Shieh, Shyh Jou MD, PhD; Lee, Jin Wei MD, EMBA; Chiu, Haw Yen MD, PhD; Ho, Chien Liang MDAuthor Information From the *Division of Plastic and Reconstructive Surgery, Department of Surgery, National Cheng Kung University Medical College and Hospital; †Division of Plastic and Reconstructive Surgery, Department of Surgery, Chi-Mei Medical Center; and ‡Institute of Clinical Medicine, National Cheng Kung University Medical College and Hospital, Tainan, Taiwan. Received October 9, 2015, and accepted for publication, after revision October 27, 2015. Conflicts of interest and sources of funding: none declared. Reprints: Chien-Liang Ho, MD, Division of Plastic and Reconstructive Surgery, Department of Surgery, National Cheng Kung University Medical College and Hospital, 138 Sheng-Li Road, Tainan, 70403, Taiwan. E-mail: firstname.lastname@example.org. Annals of Plastic Surgery: March 2016 - Volume 76 - Issue - p S35-S40 doi: 10.1097/SAP.0000000000000684 Buy Metrics Abstract Glomus tumors are rare, usually benign, vascular hamartomas consisting cells resembling the smooth muscle cells of the normal glomus body. They can be solitary or multiple, whereas solitary tumors are majorly located on the digits. Digital glomus tumors most commonly appear in subungual region and show a strong female predominance. There are several classical symptoms, clinical tests, and imaging tools, such as X-ray, magnetic resonance imaging, and ultrasonography, which can provide good accuracy for clinical diagnosis. However, misdiagnosis and delayed diagnosis are still commonly observed because primary physicians are unfamiliar with classical symptoms and clinical tests. Complete surgical excision often can result in complete relief of symptoms. Recurrence is largely caused by incomplete excision, but repeated image study is recommended to rule out new or malignant lesions. This series is a retrospective review of 50 cases with glomus tumors managed at our institute. We aim to review the key aspects of glomus tumor and provide a simple guideline for earlier diagnosis and treatment. Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved.