Aesthetic SurgeryAutologous Fat Graft by Needle Analysis of Complications After 1000 PatientsMaione, Luca MD*; Vinci, Valeriano MD*; Klinger, Marco MD*; Klinger, Francesco Maria MD†; Caviggioli, Fabio MD†Author Information From the *U.O. Chirurgia Plastica, Dipartimento di Medicina Traslazionale, IRCCS Istituto Clinico Humanitas, Università degli Studi di Milano, Rozzano; and †U.O.C. Chirurgia Plastica, IRCCS Multimedica, Università degli Studi di Milano, Sesto San Giovanni, Milan, Italy. Received July 8, 2013, and accepted for publication, after revision, October 17, 2013. Conflicts of interest and sources of funding: none declared. Devices used in this study: Coleman’s original kit for lipostructure, 18 G needle, Cordis, a Johnson & Johnson Company, NV, 9301 LJ, Roden, Netherlands. Reprints: Fabio Caviggioli, MD, Università degli Studi di Milano, Unità Operativa di Chirurgia Plastica, MultiMedica Holding SpA, Via Milanese 300, 20099 Sesto San Giovanni, Milan, Italy. E-mail: firstname.lastname@example.org. Devices used in this study: Coleman’s original kit for lipostructure, 18 G needle, Cordis, a Johnson & Johnson Company, NV, 9301 LJ, Roden, Netherlands. Annals of Plastic Surgery: March 2015 - Volume 74 - Issue 3 - p 277-280 doi: 10.1097/SAP.0000000000000050 Buy Metrics Abstract Autologous fat graft is becoming a widely used procedure in plastic surgery. Its indications are progressively increasing, ranging from functional to aesthetic surgery. The procedure has now entered in the field of regenerative medicine. Although many have commented on the long-term safety implications of fat grafting, especially to the breast, there is no body of information in the literature that analyzes near-term complications associated with this procedure. We performed a retrospective study of 1000 consecutive fat transplantation cases in our hospital since 2005. Complications were divided between donor-site complications and recipient-site complications. Of 1000 procedures, there were 2 donor-site hematomas and 83 local deformities caused by liposuction. In treated patients, the recipient site, there were 4 infections. One patient reported implant rupture at 1 month after fat graft. There was no skin necrosis in the grafted areas and no systemic complications such as pulmonary embolism, cardiac arrest, or deep venous thrombosis. The complications in fat transplantation are dominated by complications of the liposuction—the donor harvesting phase of the procedure. The relatively low complication rates in the recipient site suggest that fat transplantation, especially considering the recipient, is characterized by a high safety level and our device is simple to use. Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.