This study was designed to introduce the key points about the transplantation of lower abdominal flap with vascularized lymph node and to evaluate the effect of breast restoration, breast reconstruction, and lymphatic transplantation to treat upper limb lymphedema after breast cancer surgery.
The study was based on the retrospective study on 10 cases of postmastectomy lymphedema during January 2008 to March 2011. All patients, aged 36 to 50 years, have had one-side upper-limb lymphedema for 3 to 5 years. Six patients had accepted radiotherapy. Four patients had a diagnosis of severe lymphedema, and 2 patients had moderate lymphedema. The isotope radiography before the operation showed obstruction of lymphatic return, and the multidetector computed tomography that followed delivered a clear picture of the abdominal flap blood supply and the blood vessels in the breasts. During the operation, the scar contracture of the axilla was completely relaxed, and all patients accepted abdominal transplantation of lower abdominal flap with vascularized lymph node. After the operation, the elastic bandages were applied for one year as an adjuvant therapy. The follow-up visits were conducted 1, 3, 6, and 12 months after the surgery. The measurement indexes included mid-upper arm circumference, clinical symptoms, and lymphoscintigraphy.
All flaps worked well. One patient was found to have delayed wound healing; one patient saw no obvious improvement in lymphedema; 7 patients with lymphedema were relieved with apparent improvement in the affected limbs’ mean perimeter and clinical symptoms; one patient recovered; and another patient was lost to follow-up. The mean reduction was 2.122 ± 2.331 cm, and the reduction of the lymphedematous limb was statistically significant between the preoperative and 12-month postoperative groups (P < 0.05). The results were good in 4 patients and excellent in one patient.
The transplantation of abdominal flap with vascularized lymph node and breast reconstruction, accompanied by the treatment to upper limb lymphedema and using elastic bandages as an adjuvant therapy, is considered to be an effective method to restore the configuration and function of breasts. Long-term follow-up visits are undergoing, especially the lymphoscintigraphy, 2 years after the operation.
From the *Breast Plastic and Reconstructive Surgery Center, Plastic Surgery Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Shi-Jin-Shan District, Beijing, PR China; †Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, PR China; ‡Lu He Hospital, Capital Medical University, Beijing, PR China; §Affiliated Hospital of Hainan Medical College, Haikou, Hainan PR China; ∥Hainan Provincial People’s Hospital, Haikou, Hainan PR China; ¶Hainan Provincial Nong Ken Hospital, Haikou, Hainan PR China; #Yunnan Provincial Cancer Hospital, the 3rd Affiliated Hospital of Kunming Medical College, Kunming, Yunnan PR China; and **Service de Chirurgie Thoracique, Hôpital Europé en Georges Pompidou, Paris, France.
Received May 25, 2014, and accepted for publication, after revision, July 9, 2014.
Conflicts of interest and sources of funding: none declared.
This work was funded by Capital Clinical Characteristic Research Funding (Z111107058811097).
Reprints: Lan Mu, MD, PhD, Breast Plastic and Reconstructive Surgery Center, Plastic Surgery Hospital, Chinese Academy of Medical Science And Peking Union Medical College, Beijing 100144, China. Email: Lanhu_mu@yahoo.com.