Head and Neck SurgeryScalp Defect Repair A Comparative Analysis of Different Surgical TechniquesMueller, Cornelia Katharina, MD*; Bader, Rolf-Dieter, MD, DMD*; Ewald, Christian, MD, PhD†; Kalff, Rolf, MD, PhD†; Schultze-Mosgau, Stefan, MD, DMD, PhD*Author Information From the Departments of *Oral and Maxillofacial Surgery/Plastic Surgery, and †Neurosurgery, School of Medicine, University of Jena, Germany. Received January 8, 2011, and accepted for publication, March 6, 2011. Conflicts of interest and sources of funding: none declared. Reprints: Cornelia Katharina Mueller, MD, Department of Oral and Maxillofacial Surgery/Plastic Surgery, Friedrich-Schiller-University, Erlanger Allee 101, D-07747 Jena, Germany. E-mail: [email protected]. Annals of Plastic Surgery: June 2012 - Volume 68 - Issue 6 - p 594-598 doi: 10.1097/SAP.0b013e318218f32a Buy SDC Metrics Abstract Scalp defects often arise in multimorbid patients. This study aimed at establishing an algorithm of defect repair with particular focus on new regenerative options. All patients, who consulted to the Department of Oral and Maxillofacial Surgery/Plastic Surgery, University Jena between April 2005 and March 2010 were reviewed. Different reconstructive options were compared with regard to duration of hospital stay as well as rate of reoperations needed to achieve full closure. Sixty-eight patients were identified. Local flaps were more effective than skin grafts (P = 0.038) and microvascular free flaps (P = 0.037) in case of skin-galea-periosteal-defects. However, no differences were found between skin grafting in combination with wound bed preconditioning using a dermal regeneration template and microvascular free flap transfer. Scalp defects should be repaired based on careful evaluation of defect anatomy as well as patient’s general health. Application of dermal regeneration templates allows for an increase of the indication spectrum of free skin grafts. Copyright © 2012 Wolters Kluwer Health, Inc. All rights reserved.