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Palmoplantar Keratoderma: Treatment With CO2 Laser Case Report and Review of the Literature

O'Connor, Elizabeth A. MD; Dzwierzynski, William W. MD

doi: 10.1097/SAP.0b013e3182085a8b
Review Article

Palmoplantar keratoderma is a heterogeneous group of disorders affecting keratinization on the palms and soles of the feet. The benign lesions cause pain and limit function. Treatment of palmoplantar keratoderma remains problematic and restricted to symptomatic therapy; no cure exists. Medical treatments and surgical excision are currently the mainstay of therapy; however, these treatments have limited success, significant morbidity, and recurrence is common. We present a case report of successful treatment with CO2 laser therapy and a review of the literature.

From the Department of Plastic Surgery, Froedtert Memorial Lutheran Hospital, Milwaukee, WI.

Received August 4, 2010, and accepted for publication, after revision, November 13, 2010.

Conflicts of interest and sources of funding: none declared.

Reprints: William Dzwierzynski, MD, Department of Plastic Surgery, Froedtert Memorial Lutheran Hospital, 8700 Watertown Plank Road, Milwaukee, WI 53226. E-mail:

© 2011 Lippincott Williams & Wilkins, Inc.