Hand Surgery and MicrosurgeryCompartment Syndrome After Closure of the Anterolateral Thigh Flap Donor Site: A Report of Two CasesAddison, Patrick D. MD, MB, ChB, FRCS (Plast); Lannon, Declan MSc, FRCSI; Neligan, Peter C. MD, FRCS, FACSAuthor Information From the Department of Reconstructive Surgery, Toronto General Hospital, Toronto, Canada. Received April 16, 2007 and accepted for publication June 19, 2007. Reprints: Dr Patrick Addison, Toronto General Hospital, 200 Elizabeth Street, 8N-865, Toronto, M5G 2C4. E-mail: [email protected]. Annals of Plastic Surgery: June 2008 - Volume 60 - Issue 6 - p 635-638 doi: 10.1097/SAP.0b013e3181453b7a Buy Metrics Abstract Two male sarcoma patients developed a compartment syndrome in the thigh after the harvest and direct closure of the anterolateral thigh flap donor site. In each case, the absence of signs or symptoms led to a delay in diagnosis and treatment. Although use of the anterolateral thigh flap is increasingly popular for soft tissue reconstruction, this complication has not yet been reported. The cases and likely etiological factors are discussed as are recommendations for avoiding this devastating complication. © 2008 Lippincott Williams & Wilkins, Inc.