Original ArticleIntraoperative Lymphography Using Indocyanine Green Dye for Near-Infrared Fluorescence Labeling in LymphedemaOgata, Fusa MD*; Narushima, Mitsunaga MD*; Mihara, Makoto MD*; Azuma, Ryuichi MD†; Morimoto, Yuji MD, PhD‡; Koshima, Isao MD*Author Information From *Plastic and Reconstructive Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, Japan; and †Plastic Surgery, and ‡Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Saitama, Japan. Received September 28, 2006, and accepted for publication, after revision, October 31, 2006. Reprints: Fusa Ogata, MD, Plastic and Reconstructive Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. E-mail: [email protected]. Annals of Plastic Surgery: August 2007 - Volume 59 - Issue 2 - p 180-184 doi: 10.1097/01.sap.0000253341.70866.54 Buy Metrics AbstractIn Brief A new method for easy detection of functional lymphatic vessels in the superficial layer is reported. In a clinical trial, lymphography using indocyanine green dye for near-infrared fluorescence labeling in lymphaticovenular anastomoses was performed in 5 patients with lymphedema. The technique is simple and enables a minimally invasive operation to be performed. The results indicate that this technique is useful for acceptance as one of the examinations to evaluation of lymphedema. Intraoperative lymphography with indocyanine green dye for near-infrared fluorescence was performed on 5 patients. The study identified suitable locations for microvascular lymphaticovenular anastomoses. © 2007 Lippincott Williams & Wilkins, Inc.