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Isolated and Syndromic Syngnathism: Management, Implications, and Genetics

Tomlinson, Jillian K. MBBS(Hons), Dip Anat*; Liem, Nguyen Thanh MD, PhD; Savarirayan, Ravi MBBS, FRACP, MD, ARCPA; Meara, John G. FRACS, MBA§

doi: 10.1097/
Case Report

We present 2 contrasting cases of congenital interalveolar synechiae. The first occurred in the setting of Van der Woude syndrome and was associated with a cleft palate. In the second case, it was an isolated abnormality and there was no contributory family history or syndromic associations. We review the literature on interalveolar synechiae and discuss its management, implications, and genetics. Interalveolar synechiae is a condition with an excellent prognosis; its presence necessitates careful examination for associated abnormalities and syndromes.

From the *Royal Children's Hospital Melbourne; †National Hospital of Pediatrics, Hanoi; ‡Murdoch Children's Research Institute and Department of Paediatrics, University of Melbourne; and the §Royal Children's Hospital Melbourne, Australia.

Received November 23, 2005, and accepted for publication January 30, 2006.

Reprints: Dr Jillian Tomlinson, 8 Maple Crescent, Camberwell 3124, Victoria, Australia. E-mail:

© 2006 Lippincott Williams & Wilkins, Inc.