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Clinical, Radiological, and Audiological Relationships in Hemifacial Microsomia

Wan, Jennifer BA; Meara, John G. MD, DMD; Kovanlikaya, Arzu MD; Nelson, Marvin D. MD; Don, Debra MD

doi: 10.1097/01.SAP.0000058509.87198.EF
Original Articles
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Hemifacial microsomia is a craniofacial disorder involving structures derived from the first and second brachial arches. Bony structures, soft tissue, and the facial nerve can all be hypoplastic or absent. In this retrospective study of 70 patients at the Children's Hospital Los Angeles, craniofacial dysmorphology, temporal bone computed tomography, and audiological evaluations were examined. The purpose of this study was to identify further relationships between clinical findings, temporal bone anatomy, and audiological findings in these patients. Significant relationships were identified between total radiographic score and overall clinical findings (p < 0.001). Clinical measurements of mandibular hypoplasia were also predictive of temporal computed tomographic findings (p < 0.001), whereas clinical ear findings were related specifically to specific temporal bone abnormalities such as hypoplasia of the middle ear (p = 0.008) and fusion or absence of ossicles (p < 0.001). Interestingly, neither clinical findings nor temporal bone computed tomographic findings were related to either hearing loss type or degree. Audiology should not be deferred on the basis of relatively mild clinical findings.

A study of 70 patients with hemifacial microsomia demonstrated significant correlation between radiographic, audiologic, and clinical findings. However, neither clinical nor temporal bone CT findings were related to type or degree of hearing loss, suggesting that audiology should not be deferred in the face of mild clinical findings.

From the Childrens Hospital Los Angeles, CA.

Received October 17, 2002 and

in revised form December 13, 2002.

Accepted for publication December 13, 2002.

Address correspondence and reprint requests to Dr. Meara, Director, Department of Plastic and Maxillofacial Surgery, Royal Children's Hospital, Flemington Road, Parkville, VIC 3052, Australia.

Wan J, Meara JG, Kovanlikaya A, Nelson MD, Don D. Clinical, radiological, and audiological relationships in hemifacial microsomia.

© 2003 Lippincott Williams & Wilkins, Inc.