This study reports the use of computer-assisted sensorimotor testing in 75 patients with chronic peripheral nerve compression. Pinch and grip strength, and the cutaneous pressure threshold were measured. The reliability of this equipment for repeated measurements was excellent (r = 0.95). The pressure threshold at which a one-point static stimulus could be distinguished from a two-point static stimulus was found to be the first variable to become abnormal with computer-assisted sensorimotor testing. Criteria are suggested for screening with this equipment to detect carpal and/or cubital tunnel syndrome.