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Slingluff Craig L. Jr. MD; Seigler, Hilliard F. MD
Annals of Plastic Surgery: January 1992
Immunotherapy for Malignant Melanoma: PDF Only

Specific active immunotherapy for melanoma has been administered to several thousand patients since 1972, using an irradiated whole-cell preparation. A humoral response to vaccination can be demonstrated in a large percentage of patients. This response increases while immunizations are continued and decreases after cessation of therapy. The vaccinations are well tolerated; however, the therapeutic impact of this whole-cell vaccine awaits a randomized trial for definitive evaluation.

© Williams & Wilkins 1992. All Rights Reserved.