In Brief:
Patients from 5 institutions undergoing SILC were matched with those undergoing MLC for gender, age, disease, surgery, BMI, and surgeon. The primary endpoint was length of stay; secondary endpoints included operative time, conversion, complications, and postoperative pain scores. Among 330 patients (SILC = 165, MLC = 165) outcomes were similar to MLC, except for a reduction in peak pain score on the first postoperative day.