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Improved Outcomes of Bile Duct Injuries in the 21st Century

Pitt, Henry A. MD*; Sherman, Stuart MD; Johnson, Matthew S. MD; Hollenbeck, Andrew N. BS*; Lee, Jonathan MD*; Daum, Michael R. BS*; Lillemoe, Keith D. MD§; Lehman, Glen A. MD

doi: 10.1097/SLA.0b013e3182a1b25b
Papers of the 133rd ASA Annual Meeting

Objective: The objectives of this analysis were to compare the outcomes of bile duct injuries by specialist over time and the role of management timing and biliary stents.

Background: Postoperative bile duct injuries require multidisciplinary management. In recent years, advancements have occurred in patient evaluation and in timing and type of therapy.

Methods: A multidisciplinary team managed 528 patients over 18 years. Mean age was 52 years; 69% were women and 95% had a cholecystectomy and/or bile duct exploration. Patients were classified by the Strasberg system as having bile leaks (type A, n = 239, 45%) or bile duct injuries (types B-E, n = 289, 55%). Injury outcomes from 1993 to 2003 (n = 132) were compared with those from 2004 to 2010 (n = 157). A successful outcome was defined as no need for further intervention after the initial 12 months of therapy. Standard statistical methods were employed.

Results: Patients with bile leaks were managed almost exclusively by endoscopists (96%) with a 96% success rate. Patients with bile duct injuries were managed most often by endoscopists (N = 115, 40%) followed by surgeons (N = 104, 36%) and interventional radiologists (N = 70, 24%). Overall success rates were best for surgery (88%, P < 0.05) followed by endoscopy (76%) and interventional radiology (50%) and improved over time (78% vs 69%). Outcomes were best for surgery in recent years (95% vs 80%, P < 0.05) and for patients stented for more than 6 months (P < 0.01).

Conclusions: Almost all bile leaks and many bile duct injuries can be managed successfully by endoscopists. Selected proximal injuries can be treated by interventional radiologists with modest success. Outcomes of bile duct injuries are best with surgical management and in patients who are stented for more than 6 months.

Postoperative bile duct injuries are best managed by a multidisciplinary approach. Outcomes are best for surgery (88%) followed by endoscopy (76%) and interventional radiology (50%). Patients stented for more than 6 months had significantly better outcomes as did surgical patients in recent years.

*Department of Surgery;

Division of Gastroenterology;

Department of Radiology, Indiana University School of Medicine, Indianapolis; and

§Department of Surgery, Massachusetts General Hospital, Harvard University, Boston, MA.

Reprints: Henry A. Pitt, MD, Temple University Health System, 3509 N. Broad Street, Boyer Pavilion, E938, Philadelphia, PA 19140. E-mail: Henry.Pitt@tuhs.temple.edu.

Disclosure: The authors declare no conflicts of interest.

© 2013 by Lippincott Williams & Wilkins.