BRIEF CLINICAL REPORTSAgonist-antagonist Myoneural Interfaces in Above-knee Amputation Preserve Distal Joint Function and PerceptionSrinivasan, Shriya S. PhD∗,†,§; Herr, Hugh M. PhD∗; Clites, Tyler R. PhD∗,†; Gutierrez-Arango, Samantha BS∗; Teng, Ashley∗; Beltran, Luis MD‡; Song, Hyungeun MS∗,†,§; Israel, Erica BS∗; Carty, Matthew J. MD∗,‡,§ Author Information ∗MIT Center for Extreme Bionics, Massachusetts Institute of Technology, Cambridge, MA †Harvard-MIT Division of Health Sciences and Technology (HST), Massachusetts Institute of Technology, Cambridge, MA ‡Department of Plastics and Reconstructive Surgery, Brigham and Women's Hospital, Boston, MA §Harvard Medical School, Boston, MA. [email protected], [email protected]. Funding support was provided by the Congressionally Directed Medical Research Program. This study was carried out in full compliance with protocols approved by Partners IRB (protocol p2014001379) and MIT COUHES (protocol 1609692618). Conflicts of interest: Dr. Herr has a consulting relationship with Ottobock. Drs. Herr and Carty are inventors on an issued patent describing the AMI concept. Drs. Herr, Carty, Clites, and Srinivasan are inventors on a pending patent describing the Ewing procedure. MIT holds both patents. None of the other authors has a financial interest in any of the products, devices, or drugs mentioned in this article. Clinical Trial registered as “Somatotopic Configuration of Distal Residual Limb Tissues in Lower Extremity Amputations,” NCT03374319. Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.annalsofsurgery.com). Annals of Surgery: March 2021 - Volume 273 - Issue 3 - p e115-e118 doi: 10.1097/SLA.0000000000004153 Buy SDC Metrics Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.