Original StudyPrehospital Intravenous Fluid Administration Is Associated With Higher Mortality in Trauma Patients A National Trauma Data Bank AnalysisHaut, Elliott R. MD*; Kalish, Brian T. BA*; Cotton, Bryan A. MD, MPH†; Efron, David T. MD*; Haider, Adil H. MD, MPH*,‡; Stevens, Kent A. MD, MPH*,‡; Kieninger, Alicia N. MD§; Cornwell, Edward E. III MD¶; Chang, David C. MBA, MPH, PhD‖Author Information * Division of Acute Care Surgery, Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD; † Department of Surgery and The Center for Translational Injury Research, The University of Texas Health Science Center at Houston, Houston, TX; ‡ Department of Health Policy and Management, The Johns Hopkins University Bloomberg School of Public Health; § Department of Surgery, Washington University School of Medicine, St. Louis, MO; ¶ Department of Surgery, Howard University College of Medicine, Washington, DC; ‖ Director of Outcomes Research, Department of Surgery, University of California San Diego, San Diego, CA. Reprints: Elliott R. Haut, MD, FACS, Division of Acute Care Surgery, Department of Surgery, The Johns Hopkins Hospital, 600 N. Wolfe St., 625 Osler, Baltimore, MD 21287. E-mail: [email protected]. Financial Disclosures: none This work was presented at the Eastern Association for the Surgery of Trauma (EAST) Annual Meeting, Orlando, FL, on January 16, 2009. Annals of Surgery: February 2011 - Volume 253 - Issue 2 - p 371-377 doi: 10.1097/SLA.0b013e318207c24f Buy Metrics In Brief This retrospective, cohort study utilizing the National Trauma Data Bank shows that prehospital intravenous catheter placement and fluid administration is associated with higher mortality in trauma patients. Multivariate analysis demonstrated that patients who received an intravenous catheter and/or fluids were significantly more likely to die than those who did not (OR 1.11, 95% CI 1.05–1.17). Copyright © 2011 Wolters Kluwer Health, Inc. All rights reserved.