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SINK JAMES D. M.D.; KRAMER, STEPHEN A. M.D.; COPELAND, DANA D. M.D.; SEIGLER, H. F. M.D.
Annals of Surgery: July 1978
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Cloacogenic carcinoma is a rare tumor of the anorectal region originating from a persistant remnant of the cloacal membrane of the embryo. The tumor accounts for 2–3% of anorectal carcinomas and occurs more than twice as often in women. Most tumors present as fungating or ulcerating lesions, but the tumor may arise in anal ducts and present as a submucosal mass. Wide abdominoperineal resection is the treatment of choice with a five year survival of 50%. Metastases occurs to the inguinal lymph nodes in more than 50% of the patients at sometime during the course of the disease with distant metastases occurring most commonly to the liver and lungs.

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