In Brief:
IMPLICATIONS: In this preliminary dose-finding study, we found that a nicotine patch delivering 7–21 mg/d applied for 16 h resulted in a reduction in a patient's numerical rating scale score for up to 5 days, but without any reduction in opiate delivery or side effects compared with placebo. This information warrants a much larger study to establish the optimal dose, safety, and efficacy of a nicotine patch in postoperative pain management.
Go to Full Text of this Article