IMPLICATIONS: Variations in cerebral arteriolar were induced by hyperventilation and by increasing blood pressure to stimulate the cerebral autoregulatory response. The apparent zero flow pressure and the resistance area product both increased when arteriolar tone was expected to increase. These results imply that variations in arteriolar tone control cerebral blood flow by altering both effective downstream pressure and vascular resistance. The changes in resistance appeared to have a greater influence on cerebral blood flow than the changes in effective downstream pressure.
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