Secondary Logo

Journal Logo

Sad News for Length of Stay

The Impact of Anxiety and Depression

Wanderer, Jonathan P., MD, MPhil; Nathan, Naveen, MD

doi: 10.1213/ANE.0000000000003997
Infographics: Infographic

Vanderbilt University School of Medicine (

Northwestern University Feinberg School of Medicine (

Published ahead of print 20 November 2018.

The Infographic is composed by Jonathan P. Wanderer, MD, MPhil, Vanderbilt University School of Medicine (, and Naveen Nathan, MD, Northwestern University Feinberg School of Medicine ( Illustration by Naveen Nathan, MD.

The authors declare no conflicts of interest.



Hospital length of stay is a common and important key performance indicator for delivering perioperative care. Understanding drivers for increased hospital length of stay can lead to the identification of risk factors in advance, and potentially the implementation of mitigation strategies, which can be beneficial for patients and hospitals alike. Anxiety and depression are 2 diseases that can impact perioperative care, as they can signal difficult pain management and altered coping mechanisms. In this infographic, we review a large database study that analyzed the impact of taking antidepressants or anxiolytics preoperatively on postprocedure hospital length of stay.

IRR indicates incident rate ratio; MAOI, monoamine oxidase inhibitor; SNRI, serotonin and norepinephrine reuptake inhibitor; SSRI, selective serotonin reuptake inhibitor; TCA, tricyclic antidepressant.

Back to Top | Article Outline


1. Vashishta R, Kendale SM. Relationship between preoperative antidepressant and antianxiety medications and postoperative hospital length of stay. Anesth Analg. 2019;128:248255.
    © 2019 International Anesthesia Research Society