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Letters to the Editor: Letters & Announcements

Editor's Note

Notices of Retraction

Shafer, Steven L. MD; Editor-in-Chief

Author Information
doi: 10.1213/ANE.0b013e31821a8542
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In 2009, Dr. Joachim Boldt published a manuscript in Anesthesia & Analgesia comparing albumin and hydroxyethyl starch priming cardiopulmonary bypass.1 A subsequent review by Landesärztekammer Rheinland-Pfalz (LÄ#K-RLP), the State Medical Association of Rheinland-Pfalz, determined that there was no IRB approval for the study. The article was retracted in December 2010.2

In response to the concerns regarding IRB approval LÄ#K-RLP investigated 103 additional manuscripts that included Dr. Boldt as a coauthor, including 23 manuscripts published in Anesthesia & Analgesia. Of these 23 articles, LÄ#K-RLP was able to verify IRB approval for only one.3 LÄ#K-RLP was unable to document IRB approval for the remaining 22 articles.425

Research without IRB approval is a violation of human rights. As described in our Guide for Authors,26 and a recent editorial,27Anesthesia & Analgesia requires IRB approval for all human research. There are no exceptions. The 22 manuscripts published by Dr. Boldt for which IRB approval has not been confirmed by LÄ#K-RLP are hereby retracted for unethical conduct of research.

According to our publisher, the programs that link papers to retraction notices require a unique document identification number for each paper retracted. Therefore, this issue of Anesthesia & Analgesia contains 22 individual retraction notices representing the individual articles for which IRB approval has not been verified.

Steven L. Shafer, MD

Editor-in-Chief, Anesthesia & Analgesia

Professor of Anesthesiology, Columbia University

REFERENCES

1. Boldt J, Suttner S, Brosch C, Lehmann A, Röhm K, Mengistu A. Cardiopulmonary bypass priming using a high dose of a balanced hydroxyethyl starch versus an albumin-based priming strategy. Anesth Analg 2009;109:1752–62
2. Shafer SL. Notice of Retraction. Anesth Analg 2010; 111:1567
3. Röhm KD, Mengistu A, Boldt J, Mayer J, Beck G, Piper SN. Renal integrity in sevoflurane sedation in the intensive care unit with the anesthetic-conserving device: a comparison with intravenous propofol sedation. Anesth Analg 2009;108:1848–54
4. Riesmeier A, Schellhaass A, Boldt J, Suttner S. Crystalloid/colloid versus crystalloid intravascular volume administration before spinal anesthesia in elderly patients: the influence on cardiac output and stroke volume. Anesth Analg 2009;108:650–4
5. Boldt J, Brosch Ch, Röhm K, Lehmann A, Mengistu A, Suttner S. Is albumin administration in hypoalbuminemic elderly cardiac surgery patients of benefit with regard to inflammation, endothelial activation, and long-term kidney function? Anesth Analg 2008;107:1496–503
6. Mayer J, Boldt J, Wolf MW, Lang J, Suttner S. Cardiac output derived from arterial pressure waveform analysis in patients undergoing cardiac surgery: validity of a second generation device. Anesth Analg 2008;106:867–72
7. Mengistu AM, Röhm KD, Boldt J, Mayer J, Suttner SW, Piper SN. The influence of aprotinin and tranexamic acid on platelet function and postoperative blood loss in cardiac surgery. Anesth Analg 2008;107:391–7
8. Boldt J, Wolf M, Mengistu A. A new plasma-adapted hydroxyethylstarch preparation: in vitro coagulation studies using thrombelastography and whole blood aggregometry. Anesth Analg 2007;104:425–30
9. Mayer J, Boldt J, Schellhaass A, Hiller B, Suttner SW. Bispectral index-guided general anesthesia in combination with thoracic epidural analgesia reduces recovery time in fast-track colon surgery. Anesth Analg 2007;104:1145–9
10. Boldt J, Schölhorn T, Mayer J, Piper S, Suttner S. The value of an albumin-based intravascular volume replacement strategy in elderly patients undergoing major abdominal surgery. Anesth Analg 2006;103:191–9
11. Mayer J, Boldt J, Röhm KD, Scheuermann K, Suttner SW. Desflurane anesthesia after sevoflurane inhaled induction reduces severity of emergence agitation in children undergoing minor ear-nose-throat surgery compared with sevoflurane induction and maintenance. Anesth Analg 2006;102:400–4
12. Suttner S, Lang K, Piper SN, Schultz H, Röhm KD, Boldt J. Continuous intra- and postoperative thoracic epidural analgesia attenuates brain natriuretic peptide release after major abdominal surgery. Anesth Analg 2005;101:896–903
13. Boldt J, Brosch C, Lehmann A, Suttner S, Isgro F. The prophylactic use of the beta-blocker esmolol in combination with phosphodiesterase III inhibitor enoximone in elderly cardiac surgery patients. Anesth Analg 2004;99:1009–17
14. Suttner S, Piper SN, Kumle B, Lang K, Röhm KD, Isgro F, Boldt J. The influence of allogeneic red blood cell transfusion compared with 100% oxygen ventilation on systemic oxygen transport and skeletal muscle oxygen tension after cardiac surgery. Anesth Analg 2004;99:2–11
15. Boldt J, Brenner T, Lang J, Kumle B, Isgro F. Kidney-specific proteins in elderly patients undergoing cardiac surgery with cardiopulmonary bypass. Anesth Analg 2003;97:1582–9
16. Lehmann A, Karzau J, Boldt J, Thaler E, Lang J, Isgro F. Bispectral index-guided anesthesia in patients undergoing aortocoronary bypass grafting. Anesth Analg 2003;96:336–43
17. Boldt J, Haisch G, Suttner S, Kumle B, Schellhase F. Are lactated Ringer's solution and normal saline solution equal with regard to coagulation? Anesth Analg 2002;94:378–84
18. Lehmann A, Boldt J, Thaler E, Piper S, Weisse U. Bispectral index in patients with target-controlled or manually-controlled infusion of propofol. Anesth Analg 2002;95:639–44
19. Piper SN, Röhm KD, Maleck WH, Fent MT, Suttner SW, Boldt J. Dolasetron for preventing postanesthetic shivering. Anesth Analg 2002;94:106–11
20. Lang K, Boldt J, Suttner S, Haisch G. Colloids versus crystalloids and tissue oxygen tension in patients undergoing major abdominal surgery. Anesth Analg 2001;93:405–9
21. Haisch G, Boldt J, Krebs C, Kumle B, Suttner S, Schulz A. The influence of intravascular volume therapy with a new hydroxyethyl starch preparation (6% HES 130/0.4) on coagulation in patients undergoing major abdominal surgery. Anesth Analg 2001;92:565–71
22. Piper SN, Maleck WH, Boldt J, Suttner SW, Schmidt CC, Reich DG. A comparison of urapidil, clonidine, meperidine and placebo in preventing postanesthetic shivering. Anesth Analg 2000;90:954–7
23. Suttner SW, Schmidt CC, Boldt J, Hüttner I, Kumle B, Piper SN. Low-flow desflurane and sevoflurane anesthesia minimally affect hepatic integrity and function in elderly patients. Anesth Analg 2000;91:206–12
24. Suttner S, Boldt J, Schmidt C, Piper S, Kumle B. Cost analysis of target-controlled infusion-based anesthesia compared with standard anesthesia regimens. Anesth Analg 1999;88:77–82
25. Suttner SW, Boldt J, Schmidt CC, Piper SN, Schuster P, Kumle B. The effects of sodium nitroprusside-induced hypotension on splanchnic perfusion and hepatocellular integrity. Anesth Analg 1999;89:1371–7
26. 2010 Anesthesia & Analgesia Guide for Authors, Anesth Analg 111:525–538
27. Shafer SL. Anesthesia & Analgesia Policy on Institutional Review Board Approval and Informed Consent for Research. 2011;112:494–495
© 2011 International Anesthesia Research Society