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Featured Articles: Infographic

Handle with Intensive Care: Frailty in the Critically Ill

Wanderer, Jonathan P. MD, MPhil; Nathan, Naveen MD

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doi: 10.1213/ANE.0000000000004820
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Frailty is a multidimensional, complex syndrome that is characterized by reductions in both physiological and psychological reserve that creates a state of vulnerability. Multiple models have been proposed to measure frailty, each from a different perspective, and backed by various lines of evidence. Identification of frailty is critical in understanding what supportive care can be provided. In this infographic, we describe a recent review of the frailty literature with respect to critical care, show the most common scale used to assess frailty in the intensive care unit (ICU), provide data regarding outcomes for those patients, and review what work has been performed on interventions.

CI indicates confidence interval; ICU, intensive care unit; RR, relative risk.


1. De Blasio JC, Mittel AM, Mueller AL, Ferrante LE, Kim DH, Shaefi S. Frailty in critical care medicine: a review. Anesth Analg. 2020;130:1462–1473.
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