As evidence mounts for the efficacy of sugammadex as an alternative means for neuromuscular blockade reversal, much less has been studied about its use in the pediatric population. Gaver et al1 retrospectively analyzed nearly 1000 children treated with sugammadex with age-matched historical controls who received conventional reversal with neostigmine. Observation for the rates of bradycardia, hypotension, bronchospasm, and anaphylaxis was reviewed. In addition, the efficacy of sugammadex as defined by the time interval between administration of reversal and departure from the operating room was assessed. This infographic summarizes their findings. For the full scope of their analysis, readers are strongly encouraged to review the referenced article.
1. Gaver RS, Brenn BR, Gartley A, Donahue BS. A retrospective analysis of the safety and efficacy of sugammadex versus neostigmine for the reversal of neuromuscular blockade in children. Anesth Analg. 2019;129:1124–1129.