Secondary Logo

Journal Logo

Emerging Kids, Emerging Questions: Sugammadex Versus Neostigmine in the Pediatric Population

Nathan, Naveen MD

doi: 10.1213/ANE.0000000000004394
Infographics: Infographics

Northwestern University Feinberg School of Medicine (

The Infographic is composed by Naveen Nathan, MD, Northwestern University Feinberg School of Medicine ( Illustration by Naveen Nathan, MD.

The author declares no conflicts of interest.

As evidence mounts for the efficacy of sugammadex as an alternative means for neuromuscular blockade reversal, much less has been studied about its use in the pediatric population. Gaver et al1 retrospectively analyzed nearly 1000 children treated with sugammadex with age-matched historical controls who received conventional reversal with neostigmine. Observation for the rates of bradycardia, hypotension, bronchospasm, and anaphylaxis was reviewed. In addition, the efficacy of sugammadex as defined by the time interval between administration of reversal and departure from the operating room was assessed. This infographic summarizes their findings. For the full scope of their analysis, readers are strongly encouraged to review the referenced article.

Back to Top | Article Outline


1. Gaver RS, Brenn BR, Gartley A, Donahue BS. A retrospective analysis of the safety and efficacy of sugammadex versus neostigmine for the reversal of neuromuscular blockade in children. Anesth Analg. 2019;129:1124–1129.
    Copyright © 2019 International Anesthesia Research Society