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Going With the Flow: Cerebrovascular Disease and Autoregulation

Nathan, Naveen MD

doi: 10.1213/ANE.0000000000003883
Infographics: Infographic

Northwestern University Feinberg School of Medicine (

Published ahead of print 24 September 2018.

The Infographic is composed by Naveen Nathan, MD, Northwestern University Feinberg School of Medicine ( Illustration by Naveen Nathan, MD.

The author declares no conflicts of interest.

A retrospective cohort study in this issue assesses cerebral autoregulation and associated factors with its dysfunction in patients presenting for cardiac surgery. Specifically, the investigators seek to expose relationships between preexisting large vessel and/or small vessel cerebrovascular disease and cerebral autoregulation derangement. The reader is encouraged to review this study to see how transcranial Doppler was used to assess cerebral vasoreactivity and elucidate the association of small vessel disease and impairment of cerebral autoregulation.

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1. Hogue CW, Nomura Y, Faigle R, et al. Cerebral small vessel, but not large vessel disease, is associated with impaired cerebral autoregulation during cardiopulmonary bypass: a retrospective cohort study. Anesth Analg. 2018;127:1314–1322.
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