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Ischemic Leg, Perfused Lung

A Trial of Remote Ischemic Preconditioning

Wanderer, Jonathan P., MD, MPhil; Nathan, Naveen, MD

doi: 10.1213/ANE.0000000000002310
Infographics: Infographic

Vanderbilt University School of Medicine (

Northwestern University Feinberg School of Medicine (

The Infographic is composed by Jonathan P. Wanderer, MD, MPhil, Vanderbilt University School of Medicine (, and Naveen Nathan, MD, Northwestern University Feinberg School of Medicine ( Illustration by Naveen Nathan, MD.



Performing a lobectomy frequently requires collapsing the operative lung, which may result in hypoperfusion, ischemia, and reperfusion injury that can lead to postoperative lung injury and hypoxemia. Remote ischemic preconditioning may represent a viable strategy for reducing postoperative lung injury in patients undergoing lobectomy. In this infographic, we describe recent work that assesses markers of inflammation and measurements of perfusion following a randomized, blinded exposure to remote ischemic preconditioning.

ALI indicates acute lung injury; ARDS, acute respiratory distress syndrome; FIO2, fraction of inspired oxygen; ICU, intensive care unit; OLV, one-lung ventilation; PaO2, partial pressure arterial oxygen; TLV, two-lung ventilation.

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1. García-de-la-Asunción J, Bruno L, Perez-Griera J, et alRemote ischemic preconditioning decreases oxidative lung damage after pulmonary lobectomy: a single-center randomized, double-blind, controlled trial. Anesth Analg. 2017;125:499–506.
© 2017 International Anesthesia Research Society