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From Villain to Victor: Ketamine in Acute Neurologic Injury

Nathan, Naveen MD

doi: 10.1213/ANE.0000000000002010
Infographics: Infographic

Northwestern University Feinberg School of Medicine (

This infographic is composed and illustrated by Naveen Nathan, MD, Northwestern University Feinberg School of Medicine (

The author declares no conflicts of interest.

Few drugs have consistent and reproducible benefits when treating acute neurologic injury. This infographic illustrates the pharmacologic effects of ketamine that enhance neuroprotection and promote neurocellular recovery. Currently, ketamine is considered purely investigational in the setting of neurotrauma, stroke, subarachnoid hemorrhage and status epilepticus. Furthermore, ketamine may negatively impact brain development when used during neurologic injury in pediatric patients.1

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1. Bell JD. In vogue: ketamine for neuroprotection in acute neurologic injury. Anesth Analg. 2017; 124:1237–1243.
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