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From Liquid to Solid: Evaluating Clot Strength

Wanderer, Jonathan P. MD, MPhil; Nathan, Naveen MD

doi: 10.1213/ANE.0000000000001738
Infographic: Infographic

Vanderbilt University School of Medicine (

Northwestern University Feinberg School of Medicine (

Infographic composed by Jonathan P. Wanderer, MD, MPhil, Vanderbilt University School of Medicine (, and Naveen Nathan, MD, Northwestern University Feinberg School of Medicine (

Illustration by Naveen Nathan, MD.

The authors declare no conflicts of interest.



Identification of hypercoagulable states is critical to patient care, and recent advances have been made in developing technology to measure clot strength. In this infographic, we explain the concept of shear modulus and describe several approaches for estimating this important coagulation parameter.1–3

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1. Sniecinski RM, Tanaka KASEER Sonorhoeometry: Listening to what the clot has to say.Anesth Analg20161231346–1347
2. Huang CC, Shih CC, Liu TY, Lee PYAssessing the viscoelastic properties of thrombus using a solid-sphere-based instantaneous force approach.Ultrasound Med Biol2011371722–1733
3. Ferrante EA, Blasier KR, Givens TB, Lloyd CA, Fischer TJ, Viola FA novel device for the evaluation of hemostatic function in critical care settings.Anesth Analg20161231372–1379
© 2016 International Anesthesia Research Society