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Donor Difference (Living Versus Cadaver) Rather Than Preoperative Recipient's Status Affects Transfusion Requirements in Liver Transplantation

Section Editor(s): Saidman, LawrenceKim, Gaab Soo MD; Gwak, Mi Sook MD; Ko, Justin Sang MD

doi: 10.1213/
Letters to the Editor: Letters & Announcements

Department of Anesthesiology and Pain Medicine; Samsung Medical Center; Sungkyunkwan University School of Medicine; 50, Il won-Dong, Kangnam-Ku; Seoul, Korea 135-710;

Dr. Frasco does not wish to respond.

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To the Editor:

Frasco et al. (1) found significant differences in disease severity (Model for End-Stage Liver Disease, MELD score), impairment of coagulation function, and the need for red blood cell and component transfusion between patients undergoing living and cadaveric liver transplantation. We performed a similar study which was published in Korean (2), although it appeared as an abstract in English (3). In our study, 17 patients received a cadaveric liver and 16 patients received a liver from a living donor. In contrast to the results of Frasco et al. study, we found no significant differences in the preoperative MELD score (P = 0.544, Student's t-test) or coagulation function between the groups, as shown in Table 1. We believe that the type of donor liver (living versus cadaver) rather than the recipient's preoperative status is a better predictor of reperfusion coagulopathy and intraoperative transfusion requirements.

Table 1

Table 1

Gaab Soo Kim, MD

Mi Sook Gwak, MD

Justin Sang Ko, MD

Department of Anesthesiology and Pain Medicine

Samsung Medical Center

Sungkyunkwan University School of Medicine

50, Il won-Dong, Kangnam-Ku

Seoul, Korea 135-710

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1. Frasco P, Poterack K, Hentz J, Mulligan D. A comparison of transplantation requirements between living donation and cadaveric donation liver transplantation: relationship to model of end-stage liver disease score and baseline coagulation status. Anesth Analg 2005;101:30–7
2. Shin BS, Ha IH, Kim GS, Gwak MS, Chung IS. The comparison of coagulation status in the cadaveric donor and living-related liver transplantation. Kor J Anesth 2002;43:49–57
3. Baek H, Shin B, Kim G. The comparison of coagulation status in the cadaveric donor and living-ralated liver transplantation. Anesthesiology 2004;101:A1288
© 2007 International Anesthesia Research Society