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Sedation Depth and Mortality: A Large Randomized Trial Is Required

Leslie, Kate MBBS, MD, M Epi, FANZCA*†‡§; Short, Timothy G. MBChB, MD, FANZCA

doi: 10.1213/ANE.0000000000000210
Editorials: Editorial

From the *Department of Anaesthesia and Pain Management, Royal Melbourne Hospital, Melbourne, Australia; Anaesthesia, Perioperative Medicine and Pain Medicine Unit, Melbourne Medical School and Department of Pharmacology, University of Melbourne, Melbourne, Australia; §Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia; and Department of Anaesthesiology and Perioperative Medicine, Auckland City Hospital, Auckland, New Zealand.

Accepted for publication January 29, 2104.

Funding: This work was funded by Australian National Health and Medical Research Council Project Grant APP104272 and Health Research Council of New Zealand project grant 12-308 to Dr. Short.

The authors declare no conflicts of interest.

Reprints will not be available from the authors.

Address correspondence to Kate Leslie, MBBS, MD, M Epi, FANZCA, Department of Anaesthesia and Pain Management, Royal Melbourne Hospital, Parkville, VIC, 3050, Australia. Address e-mail to

© 2014 International Anesthesia Research Society