From the *Department of Anaesthesia, National University Hospital, Singapore
†Department of Anaesthesia, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
‡Department of Anesthesiology, Section on Critical Care Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina
§Department of Anesthesiology Mayo Clinic College of Medicine and Science, Rochester, Minnesota
‖Department of Perioperative Medicine, Mayo Clinic College of Medicine and Science, Rochester, Minnesota
¶Department of Clinical Research, Patient Monitoring Clinical Research, Medtronic, Minneapolis, Minnesota
#Department of Core Clinical Solutions, Global Clinical Data Solutions, Medtronic, Rome, Italy.
Accepted for publication February 22, 2022.
Funding: Study sponsored by Medtronic, which contributed to the original study design, data collection, and analysis. The authors (or their institutions) received research support from Medtronic to conduct the PRODIGY study. The authors had access to study data and final responsibility for the decision to submit for publication. The authors were not paid to write this article by the sponsor or any other agency.
Clinical Trial Registration: www.clinicaltrials.gov NCT02811302.
Conflicts of Interest: See Disclosures at the end of the article.
Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s website (www.anesthesia-analgesia.org).
A portion of this work was accepted as an abstract for the 2021 Society of Anesthesia and Sleep Medicine Annual Meeting held virtually October 7-8, 2021.
A full list of contributors can be found at the end of the article.
Reprints will not be available from the authors.
Address correspondence to Lian Kah Ti, MBBS, MMed, FAMS, Department of Anaesthesia, Yong Loo Lin School of Medicine, National University of Singapore, 21 Lower Kent Ridge Rd, Singapore, 119077. Address e-mail to [email protected].