From the *Department of Anaesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany
†Department of Medicine, Veterans Affairs Medical Center, San Diego, California
‡Department of Anesthesia and Intensive Care, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), San Raffaele Scientific Institute, Milan, Italy
§School of Medicine, Vita-Salute San Raffaele University
‖Department of Critical Care, the University of Melbourne, Melbourne, Australia
¶Department of Intensive Care, Royal Melbourne Hospital, Parkville, Victoria, Australia
#Department of Intensive Care, Austin Health, Heidelberg, Australia
**Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia
††Institute of Biostatistics and Clinical Research, University of Münster, Münster, Germany.
Published ahead of print February 16, 2022.
Accepted for publication December 22, 2021.
Conflicts of Interest: See Disclosures at the end of the article.
Funding: The trial was supported by the German Research Foundation (KFO342-1, ZA428/18-1, and ZA428/21-1 to A.Z. and ME5413/1-1 to M.M.).
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Address correspondence to Alexander Zarbock, MD, Department of Anaesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Albert-Schweitzer-Campus 1, Geb. A1, 48149 Münster, Germany. Address e-mail to [email protected].
