From the *Department of Anesthesiology and Perioperative Care, Ramsay Santé, Sauvegarde Clinic, Lyon, France
†Department of Anesthesiology and Perioperative Care, University of California, Irvine, Irvine, California
‡Department of Anesthesiology, Brugmann Hospital, Université Libre de Bruxelles, Brussels, Belgium
§Department of Anesthesiology and Perioperative Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California
∥Department of Cardiac Surgery, Ramsay Santé, Sauvegarde Clinic, Lyon, France
¶Department of Intensive Care, Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium
#Department of Anesthesiology and Intensive Care, Hôpitaux Universitaires Paris-Sud, Université Paris-Sud, Université Paris-Saclay, Bicêtre and Paul Brousse Hospitals, Assistance Publique Hôpitaux de Paris, Villejuif, France
**Department of Anesthesiology, Erasme University Hospital, Brussels, Belgium.
Published ahead of print January 21, 2022.
Funding: Development of the closed-loop system was supported in part by the National Heart, Lung, and Blood Institute of the National Institutes of Health (NIH) under award number U54HL119893, and by NIH/National Center for Advancing Translational Sciences UL1 TR00001414 (J.R.). This work was also supported in part by NIH R01 HL144692 and R01 EB029751 (M.C.).
Conflicts of Interest: See Disclosures at the end of the article.
Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s website.
Clinical Trial Registration: ClinicalTrials.gov (NCT04586218) published on October 14, 2020 (principal investigator: Olivier Desebbe).
Reprints will not be available from the authors.
Address correspondence to Alexandre Joosten, MD, PhD, Department of Anesthesiology and Perioperative Medicine, Bicêtre Hospital, 78, Rue du General Leclerc, 94270 Le Kremlin-Bicêtre, France. Address e-mail to [email protected].
