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Postoperative Neurocognitive Disorders After Closed-Loop Versus Manual Target Controlled-Infusion of Propofol and Remifentanil in Patients Undergoing Elective Major Noncardiac Surgery: The Randomized Controlled Postoperative Cognitive Dysfunction-Electroencephalographic-Guided Anesthetic Administration Trial

Mahr, Nicolas MD*; Bouhake, Yannis MD*; Chopard, Gilles PhD; Liu, Ngai MD, PhD‡,§; Boichut, Nathalie MD*; Chazot, Thierry MD‡,§; Claveau, Melanie MD*; Vettoretti, Lucie PhD*; Tio, Gregory BSc; Pili-Floury, Sebastien MD, PhD*,¶,#; Samain, Emmanuel MD, PhD*,¶,#; Besch, Guillaume MD, PhD*,¶

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doi: 10.1213/ANE.0000000000005278

Abstract

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