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Recognizing the Chinese Pioneer of Neuraxial Labor Analgesia: Dr Guang-Bo Zhang and Her Unpublished Manuscript From More Than a Half-Century Ago

Cai, Zhen-Yu MD, MS*; Hu, Ling-Qun MD; Stellaccio, Francis S. MD; Wang, Dong-Xin MD, PhD§

doi: 10.1213/ANE.0000000000003845
Obstetric Anesthesiology

Dr Guang-Bo Zhang was the first anesthesiologist to administer and study the effects of labor epidural analgesia in China. Between September 1963 and March 1964, she conducted an observational study evaluating the effects of neuraxial analgesia for laboring women. She presented her research and prepared an article; however, due to the Great Proletarian Cultural Revolution (Cultural Revolution), which began in 1966, her work went unpublished. She successfully preserved her unpublished article, notes, and slides throughout the Cultural Revolution by hiding them in a countryside location near Beijing. These 54-year-old, previously unpublished documents represent the first known clinical trial of neuraxial labor analgesia conducted in China.

From the *Department of Obstetrics and Gynecology, Aviation General Hospital of China Medical University, Beijing, China

Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois

Department of Anesthesiology, State University of New York at Stony Brook, School of Medicine Stony Brook University, Stony Brook, New York

§Department of Anesthesiology and Critical Care Medicine, Peking University First Hospital, Beijing, China.

Accepted for publication Septermber 5, 2018.

Published ahead of print 5 September 2018.

Funding: None.

The authors declare no conflicts of interest.

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Reprints will not be available from the authors.

Address correspondence to Ling-Qun Hu, MD, Department of Anesthesiology, Northwestern University Feinberg School of Medicine, 251 E Huron St F4-701, Chicago, IL 60611. Address e-mail to

Copyright © 2018 International Anesthesia Research Society
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