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Emge Ludwig A. M.D.; Hoffman, P. E. M.D.
Current Researches in Anesthesia & Analgesia: March-April 1931

IN THE INTRODUCTION of any drug which is likely to find universal usage we must, above all, be certain that its margin of safety is such that even in the hands of the less experienced and the less cautious the effect of the drug will not create a state of serious danger to the life of the patient. Whenever dramatic and spectacular reactions overshadow dangers not easily discerned we must then make doubly sure to discover all possible sources of danger.

*Read before the Joint Meeting of the Pacific Coast Association of Anesthetists with the Section of Anesthesiology of the California Medical Association, Del Monte, Calif., April 28–29, 1930. From the Department of Obstetrics and Gynecology, Stanford University School of Medicine. Courtesy of California and Western Medicine.

© 1931 International Anesthesia Research Society