AS FAR as the general inhalation anesthetics are concerned there has not yet been a systematic effort to determine whether or not there is any relation between chemical constitution and physiological action by the chemical synthesis and pharmacological study of a relatively large series of related compounds. The chlorinated methanes (chloroform and carbon-tetra-chlorid), the alkyl ethers (methyl-ethyl ether, and di-ethyl ether), and the unsaturated hydrocarbons (ethylene, acetylene, and propylene) suggests the possibility of work along this line.
*Honorary Presidential Address presented by-proxy through the courtesy of J. Homer Wool-sey, M.D., before the Ninth Annual Congress of Anesthetists, the International Anesthesia Reseach Society in Joint Meeting with the Eastern Society of Anesthetists, Clinical Congress of Surgeons Week, Hotel Adelphia, Philadelphia, October 13–16, 1930. From the Department of Pharmacology, University of California Medical School, San Francisco.
© 1931 International Anesthesia Research Society