Brief CommentaryClear Cell Hidradenoma of the Skin—A Third Tumor Type With a t(11;19)-Associated TORC1-MAML2 Gene Fusion Genes Chromosomes Cancer. 2005;43:202–205El-Naggar, Adel K. MD, PhDAuthor Information Department of Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX Reprints: Adel K. El-Naggar, MD, PhD, Department of Pathology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd., Unit 085, Houston, TX 77030 (e-mail: [email protected]) Advances in Anatomic Pathology: March 2006 - Volume 13 - Issue 2 - p 80-82 doi: 10.1097/01.pap.0000213000.79866.bd Buy Metrics Abstract Recent cloning of the MEC-1/MAML2 gene, resulting from translocations of chromosomes 11q21 and 19p23, has for the first time linked specific genetic alterations to the development of specific salivary gland tumors. Such a unique finding in an epithelial neoplasm opens new horizons in understanding the evolution of these tumors and allows for the development of therapeutic modalities that target these events. Copyright © 2006 Wolters Kluwer Health, Inc. All rights reserved.