UPDATE ARTICLES/COMMENTARIES: PDF OnlySpurgers Kevin; Briones, Fermin; McDonnell, Timothy J.Advances in Anatomic Pathology: January-February 2000 - p 9-12 Buy Abstract Summary: There are at present very few well-characterized molecular alterations that occur at high frequency in prostate cancer. Recent evidence suggests that alterations in the pp32 family of nuclear phosphoproteins may be a common event in prostate cancer. Individual members of this gene family appear to function as either tumor suppressors or oncogenes. *At the Department of Molecular Pathology, The University of Texas, M.D. Anderson Cancer Center, Houston, Texas, U.S.A. © 2000 Lippincott Williams & Wilkins, Inc.