Original ArticlesThe Relationship Between Earlobe Creases and the Presence, Extent, and Severity of Coronary Artery Atherosclerosis A Regional Population-Based Autopsy StudyFrench, Claire E.V. PhD, MBChB, PGDipSci, BSc∗,†; Rutherford, John David BSc (Hons), MB CHB, FRCP (Edin), FRCPath, FFFLM, MSc‡; Goossens, Louise BSc, MIMI, AIMBI, MNZIMSI§; Tiemensma, Marianne MBChB, Dip For Path, FC For Path, MMed, FRCPA‡,∥Author Information From the ∗Wellington Southern Community Laboratories, Wellington Regional Hospital †Department of Molecular Medicine and Pathology, School of Medicine, University of Otago, Wellington, New Zealand ‡Forensic Pathology Unit, Royal Darwin Hospital, Tiwi, Australia §Capital and Coast District Health Board, Wellington, New Zealand ∥College of Medicine and Public Health, Flinders University, Adelaide, Australia. Manuscript received August 3, 2020; accepted November 11, 2020. The authors report no conflict of interest. Reprints: Marianne Tiemensma, MBChB, Dip For Path, FC For Path, MMed, FRCPA, Forensic Pathology Unit, Royal Darwin Hospital, 105 Rocklands Dr, Tiwi, NT 0810, Australia. E-mail: [email protected]; [email protected]. The American Journal of Forensic Medicine and Pathology: June 2021 - Volume 42 - Issue 2 - p 155-159 doi: 10.1097/PAF.0000000000000661 Buy Metrics Abstract The association between earlobe crease(s) and coronary artery atherosclerosis has stimulated debate and controversy over the years. Most available published studies have been conducted on living patients. Although these studies offer valuable insight into such associations in patients who exhibit symptoms, no information is available from these studies on the prevalence of earlobe creases among an asymptomatic population. Postmortem studies offer the advantage of including individuals free of symptomatic cardiovascular disease, thus providing an inbuilt control group. The atherosclerotic pathological findings of 1298 individuals who underwent coronial postmortem examination at Wellington Regional Hospital, New Zealand, between 2006 and 2013 were retrospectively studied. Earlobe creases and atherosclerosis involving the coronary arteries were semiquantitatively appraised. The presence of an earlobe crease was found to be significantly associated with coronary artery atherosclerosis. Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.