Original ArticlesSevere Calcific Chronic Constrictive Pericarditis as an Unexpected Cause of Death An Autopsy CaseBoussaid, Marwa MD∗,†,‡; Mesrati, Mohamed Amin MD∗,†,‡; Mahjoub, Yosra MD∗,†,‡; Limem, Hiba MD∗,†,‡; Ben Abdeljalil, Nouha MD†,‡; Zakhama, Abdelfatteh MD†,‡; Aissaoui, Abir MD∗,†,‡Author Information From the ∗Department of Forensic Medicine, University Hospital Tahar Sfar of Mahdia, Mahdia †Department of Pathology, University Hospital Fattouma Bourguiba of Monastir ‡Faculty of Medicine, University of Monastir, Monastir, Tunisia. Manuscript received November 17, 2018; accepted February 5, 2019. The authors report no conflict of interest. Reprints: Abir Aissaoui, MD, Faculty of Medicine of Monastir- University of Monastir, Department of Legal Medicine, Research Laboratory LR-12-SP, Taher Sfar Teaching Hospital, 5100 Mahdia, Tunisia. E-mail: [email protected]. The American Journal of Forensic Medicine and Pathology: September 2019 - Volume 40 - Issue 3 - p 273-274 doi: 10.1097/PAF.0000000000000478 Buy Metrics Abstract Chronic calcific constrictive pericarditis is a rare condition. It can cause severe morbidity and even mortality. The diagnosis may be difficult to establish due to its variable clinical signs. We report an autopsy case of a 54-year-old male with a past medical history of well treated hypertension, diabetes and dyspnea present of 2 weeks, who was discovered dead in his bed. The postmortem examination showed a large band of calcification of the pericardium with obliteration of the pericardial space. Both pericardium and epicardium were thickened with bread-and-butter appearance. Microscopic examination showed thickened pericadium which is formed by a fibrous paucicellular tissue containing extensive basophilic calcifications. Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.