Original ArticlesCan Intoxication Status Be Used as a Prediction Tool for Manner of Death? A Comparison of the Intoxication Status in Violent Suicides and HomicidesMolina, D. Kimberley MD; Hargrove, Veronica M. PhDAuthor Information From the Bexar County Medical Examiner's Office, San Antonio, TX. Manuscript received July 26, 2016; accepted November 20, 2016. The authors report no conflict of interest. Reprints: D. Kimberley Molina, MD, Bexar County Medical Examiner's Office, 7337 Louis Pasteur Dr, San Antonio, TX 78229. E-mail: firstname.lastname@example.org. The American Journal of Forensic Medicine and Pathology: March 2017 - Volume 38 - Issue 1 - p 69-73 doi: 10.1097/PAF.0000000000000294 Buy Metrics Abstract Determining the manner of death in medicolegal death investigations can be difficult. The investigator relies on many facets of death investigation, including the circumstances of death and autopsy examination. A study was designed to analyze whether the intoxication status of the decedent could be used as another tool in death investigations. The intoxication status of violent (nonoverdose or poisoning) suicides and homicides was retrospectively reviewed and compared. A total of 625 deaths were identified, including 366 suicides and 259 homicides. Age, sex, cause of death, and intoxication status, including the specific drugs present, were analyzed. Gunshot wounds were the most common cause of death in both groups, with hanging being the second most common cause in suicides and sharp force injuries in homicides. Analysis found that although the overall intoxication status for suicides versus homicides did not differ significantly, certain drugs were more prevalent in one group over the other. Specifically, illicit drugs, that is, heroin, cocaine, and methamphetamine, were more likely to be present in homicides, whereas antidepressants or antipsychotics, benzodiazepines, and zolpidem were more common in suicides. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.